Christine Bellanné-Chantelot Selected Research

Insulin (Novolin)

12/2020	Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
1/2020	Update of variants identified in the pancreatic β-cell KATP channel genes KCNJ11 and ABCC8 in individuals with congenital hyperinsulinism and diabetes.
1/2012	Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia.
10/2010	Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome.
11/2009	Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia.
8/2009	HNF1B-related diabetes triggered by renal transplantation.
2/2009	Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism.
1/2006	Molecular mechanisms of neonatal hyperinsulinism.
1/2005	Diagnosis and management of maturity-onset diabetes of the young.
2/2004	Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse congenital hyperinsulinism.

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Christine Bellanné-Chantelot Research Topics

Disease

11	Congenital Hyperinsulinism 01/2021 - 02/2004
10	Type 2 Diabetes Mellitus (MODY) 12/2020 - 08/2003
7	Autosomal Recessive 3 Severe Congenital Neutropenia 01/2022 - 06/2004
7	Neoplasms (Cancer) 01/2017 - 01/2005
5	Neutropenia 01/2021 - 01/2005
5	Diabetes Mellitus 10/2010 - 04/2004
4	Hypoglycemia (Reactive Hypoglycemia) 06/2018 - 11/2009
4	Hyperglycemia 11/2009 - 07/2008
4	Hyperinsulinism (Hyperinsulinemia) 02/2009 - 01/2006
3	Cyclic neutropenia 01/2021 - 06/2004
3	Thrombocytosis (Thrombocythemia) 01/2017 - 02/2014
3	Leukemia 02/2013 - 01/2005
3	Hyperplasia 10/2011 - 02/2004
3	Mason-Type Diabetes 11/2009 - 03/2005
3	Renal cysts and diabetes syndrome 07/2007 - 04/2004
2	Reinfection 10/2021 - 01/2014
2	Shwachman-Diamond Syndrome 01/2019 - 05/2011
2	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 09/2018 - 01/2015
2	Essential Thrombocythemia 01/2016 - 02/2014
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2012 - 12/2007
2	Type 2 Maturity-Onset Diabetes of the Young 07/2008 - 01/2005
2	Atrophy 01/2005 - 04/2004
1	Hearing Loss (Hearing Impairment) 01/2022
1	severe chronic Neutropenia 01/2021
1	Precocious Puberty 09/2018
1	Insulinoma 06/2018
1	Exocrine Pancreatic Insufficiency 01/2018
1	Hypersensitivity (Allergy) 01/2018
1	primary familial and congenital Polycythemia 01/2018
1	Polycythemia (Erythrocytosis) 01/2018
1	Thrombocytopenia (Thrombopenia) 01/2017
1	Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell) 01/2017
1	Proteinuria 05/2016
1	Polycythemia Vera 01/2016
1	Fatigue 01/2015
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2015
1	Wounds and Injuries (Trauma) 01/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2014
1	Cohen syndrome 05/2014
1	WHIM syndrome 01/2014
1	Inborn Genetic Diseases (Disease, Hereditary) 05/2011
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 05/2011
1	Cystic Fibrosis (Mucoviscidosis) 04/2011
1	Autistic Disorder (Autism) 10/2010
1	Spontaneous Abortion (Miscarriage) 03/2010

Drug/Important Bio-Agent (IBA)

10	Insulin (Novolin)FDA Link 12/2020 - 02/2004
7	Transcription Factors (Transcription Factor)IBA 10/2016 - 08/2003
7	Hepatocyte Nuclear Factor 1-betaIBA 10/2010 - 04/2004
6	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 10/2021 - 01/2005
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2004
6	KATP ChannelsIBA 01/2021 - 09/2007
6	GlucokinaseIBA 06/2018 - 08/2003
5	Adenosine Triphosphate (ATP)IBA 10/2016 - 09/2007
4	Hepatocyte Nuclear FactorsIBA 11/2017 - 03/2005
4	Glucose (Dextrose)FDA LinkGeneric 10/2011 - 01/2008
3	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2021 - 06/2004
3	Thrombopoietin (c-mpl Ligand)IBA 01/2017 - 02/2014
3	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 03/2007 - 01/2005
2	EnzymesIBA 01/2018 - 08/2003
2	Amino Acids FDA Link 01/2018 - 01/2008
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2015 - 03/2010
2	Octreotide (Sandostatin)FDA LinkGeneric 02/2012 - 10/2011
2	Diazoxide (Hyperstat)FDA Link 10/2011 - 10/2011
2	Sulfonylurea ReceptorsIBA 04/2011 - 02/2009
2	GlucocorticoidsIBA 03/2010 - 08/2003
2	SteroidsIBA 08/2009 - 09/2007
2	Levodopa (L Dopa)FDA LinkGeneric 12/2007 - 01/2007
1	ElementsIBA 01/2022
1	Endopeptidase ClpIBA 01/2022
1	ProinsulinIBA 12/2020
1	Peptide Elongation Factors (Elongation Factor)IBA 01/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2019
1	SaltsIBA 09/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Erythropoietin Receptors (Erythropoietin Receptor)IBA 01/2018
1	DiamondIBA 01/2018
1	Erythropoietin FDA Link 01/2018
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2017
1	4,5,6,7- tetrahydroisoxazolo(4,5- c)pyridin- 3- ol (THPO)IBA 01/2017
1	Potassium Channels (Potassium Channel)IBA 10/2016
1	intrinsic factor-cobalamin receptorIBA 05/2016
1	Low Density Lipoprotein Receptor-Related Protein-2IBA 05/2016
1	Autophagy-Related ProteinsIBA 03/2016
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2016
1	Thrombopoietin ReceptorsIBA 01/2016
1	CalreticulinIBA 01/2016
1	Cosyntropin (Cortrosyn)FDA LinkGeneric 01/2015
1	Protein Isoforms (Isoforms)IBA 06/2014
1	Membrane Proteins (Integral Membrane Proteins)IBA 05/2014
1	Mitochondrial DNA (mtDNA)IBA 05/2014
1	Phosphotransferases (Kinase)IBA 02/2014
1	Chemokine ReceptorsIBA 01/2014
1	Nonsense Codon (Nonsense Mutation)IBA 01/2014
1	Glucagon (Glukagon)FDA Link 10/2011
1	Neurofibromin 1 (Neurofibromin)IBA 05/2011
1	Guanosine Triphosphate (GTP)IBA 05/2011
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 08/2009

Therapy/Procedure

9	Therapeutics 10/2021 - 01/2005
2	Pancreatectomy 10/2011 - 12/2007
1	Antibiotic Prophylaxis 10/2021